Plates · 96 × 111
artwork-v1
༼つ◕‿◕‿⚆༽つ ...the machine reads its own hymn back into its mouth... the protein never lands, brl'zzzt...
The plate
Fig. 196 across, 111 down.
The grid itself
.
l u x · n o v a · descending
· . : | : . · . : |
___,.-~"""""""""""""""""""""""""""""""""~-.,___
_,-' .-~" C A U C A U C A U "~-. '-,_
,-' _,-~" .-' \ / \ / \ "~-,_ '-,
,' ,-" ,-' .-~"~-.\ /.-~"~-./ \.-~"~-. "-, ',
/ ,' ,' ,-' _ \()/ _ \()/ _ '-. ', \
/ ,' ,' ,' ,-' '-,/ \,-' '-,/ \,-' '-, '. '. \
/ ,' ,' / ,' ___ \ / ___ \ / ___ '. \ . '. \
/ / ,' / / ,' '.\()/.' '.\()/.' '. \ \ : \ \
/ / / | | / .--. \ / .--. \ / .--. \ | | | \ \
| / / | | | ( <> ) || ( () ) || ( <> ) || | | : \ |
| | / .--' | | '--' || '--' || '--' || | '--. : | |
| | | / the | | rose || eye || window || | | \ | |
| | | | > re-entry mouth: chain enters here < | | | | |
| | \ \ ,-~"""~-. .-~"""~-. .-~"""~-. .-~"""| / / | |
\ \ '. '-. knot \/ jgs \/ \/ .-' / / / /
\ \ '-,_ '-.~snake head meets its own tail.-' _,-' / / /
\ '-, '~-.,_ '~--..,,___,,..--~' _,.-~' _,.-~' ,-' /
\ '-,_ '~--..,,_____,,..--~~' _,.-' _,-'
'-,_ '~-.,__ __,.-~' __,.-'
____'~-.,_______'~~--..,,,,_________,,,,..--~~'______,..-~'____
|.'', '~~--..,,______________________,,..--~~' ,''.|
|.'.'', TRIFORIUM :: carved codon stonework reads down ,''.'.|
|.'.'.'', C A U :: C A U :: C A U :: C A ,''.'.'.|
|.'.'.'.'', | | | | | | | ,''.'.'.'.|
|.'.'.'.'.| G C A U A C G C A U A C G C A |.'.'.'.'.|
|.'.'.'.'.|===; | | | | | ;===|.'.'.'.'.|
|.'.'.'.'.|:::|', . : | : . : ,'|:::|.'.'.'.'.|
_.-----._ |.'.'.'.'.|---|'.| ___pipe-organ : the mRNA ___ |.'|---|.'.'.'.'.| _.-----._
( )|.'.'.'.'.|:::|'.|| .------. strand .------.||.'|:::|.'.'.'.'.|( )
|~--C-A-U~||,',',',',|---|',|| ( C A U ) ( U A C )||',|---|,',',',',||~U-A-C--~|
| ||.'.'.'.'.|:::|'.|| |~------~| .----. |~------~|||.'|:::|.'.'.'.'.|| |
| _.----._||.'.'.'.'.|---|',|| | C | ( ) | U |||','|--|.'.'.'.'.||_.----._ |
|( C A U )|.'.'.'.'.|===:' | | A | ||~--~|| | A | | ':===|.'.'.'.'.|( U A C )|
||~------~||.'.'.'.',' | | U | || || | C | | ',.'.'.'.'.||~------~|
|| the ||.'.'.',' | | .---.|| .---.| | .---. | | ',.'.'.'.|| nave ||
|| qi ||.',' C O L | | |._C_.'|| |._U_.' | |._A_.| | L U M N ',.'.'.|| of ||
|| line ||;_________U_M_N__| | | A | || | A | | | C | |__N_____;|',.','.||organ ||
||falling || ___ C | | | U | || | C | | | U | A ___ |',','.|| pipes ||
|| .:|# || .-----...----. | |.------.||.------. |.------.| .-----...----. || #|:. ||
|| .:|# ||/ .-._______.-. \ |( || ) ( )| / .-._______.-.\|| rising ||
|| .:|# ||\ ` /_____\ ` / ||~------~||~------~| |~------~|| \ ` /_____\ ` /|| #|:. ||
|| .:|# || '--'| | | |'--' || || | | || '--'| | | |'--' || #|:. ||
|| .:|# || | | | | || C A U || U A C | | C A U || | | | | || #|:. ||
|| v || | | | | ||________||________| |________|| | | | | || ^ ||
|| v || | | | | __|| | | | | __|| ^ ||
|| v || | | | | | the chain threads down through the pipes| | | | | || ^ ||
|| v || |_|_|_| | as codons, organ-stops set the reading |_|_|_| | || ^ ||
|| v || _/_______\_ | C - A - U - C - A - U - C - A - U _/_____\_| || ^ ||
\ v / | |___________||________________ | _______________________|_________| \ ^ /
\ v / | | \ ^ /
'~..~' | L A R G E S U B U N I T | S M A L L S U B U N I T '~^'
| (( W I B )) | [[ W O B ]]
,,..--""--..,,_ ___,,..--~~""~~|~~""~~--..,,___ _,,..--""--..,,
,-' the large lobe '-,_,-' ◕ ◕ ⚆ ___|___ ⚆ ◕ ◕ '-,_,-' the small lobe '-,
/ organic masonry .' ( (( WIB )) | | (( WOB )) ) '. geometric shell \
| .'.'.'.'.'.'.'.'. / ,-' ◕‿◕‿⚆ ༼つ | | つ༽ ⚆‿◕‿◕ '-, \ [#][#][#][#][#] |
| .'.'.'.'.'.'.'.'.' | / the two lobes clamp| |the active site \ | #][#][#][#][#]# |
|.'.'.'.'.'.'.'.'.'. | | ,---. .---. | | .---. ,---. | |.# #][# #][# #].|
|'.'.'.'.'.'.'.'.'.' | | ( P ) ( A ) site | | exit( E ) ( T ) | |' #][# #][# #] '|
|.'.'.'.'.'.'.'.'.'. | | '---' '---' | | '---' '---' | |.'.'.'.'.'.'.'.'|
|'.'.'. ACTIVE .'.' | | tRNA tRNA |#| peptide | |'.'.SITE .'.'.'|
\ '.'.' SITE .'.' / | \ . / \ . / __|#|__ bond forms | \ '.'.'.'.'.' /
'-,_ '.'.'.'_,-' | \./ \./ / |#| \ | | | | '-,_'.'_,-'
""""""" | C A | the WAIST | U .--codon--.--. """
| | | | tunnel: | | ( the only ) |
the polypeptide | '--. '--. | 3 columns | .' '.exit.--' | chain extruded
exits the tunnel | '-. '-| wide |-' | | here, downward
and begins to | '-. | |#| | _.-' | |
fold ......... | '-.| _|#|_ |.-' v v
| fold -> .-~"| / | \ |"~-. <- fold |
| .-~" _,'| | | | |',_ "~-. |
| .-~" _,-' | | | | | '-,_ "~-. |
| .-~" _,-' the protein chain coils, '-,_ "~-.
| ,' _,-' .---. never reaching its '-, '. |
| / ,-' .-' '-. native fold .-----. '-, \|
|/,' .-' .---. '-. .-' '-. '.|
|' .-' .' '. '-. .' .---. '-. '|
| .' .' .-. '. '. .' .' '. '. |
| ' .' .' '. '. '| .' .-. '. '|
>+< | .' ' .-. ' '. ,' ' .' '. '. | << the REBIS:
input==output | .' the ' ' ' the '. '. ' ' .-. ' '. '| in == out
same cell, the| .' loop '. '.-.' loop '. '. .' ' ' '. '| the fold IS
fold turns the| ' never '. .' closes'. ' '.-. .' ' '| the input
chain back UP \ . closes '-.,-' ,'.' ' '.' . /
into mRNA -----'\. . . . . '----------' . . . . ./'----- back up the
'-,_ ___ ___ _,-' serpent wall
,,..--~~""~~--..,,_________'~-. '~-.,,_______,,.-~' .-~'________,,..--~~""~~--..,,
| C R Y P T :: the protein never finishes folding :: C R Y P T :: |
|.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.|
|.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.|
|'.'. _.-~~~-._ .-------------------------------. _.-~~~-._ '.'|
|.'. ,' fold '. | F O L D - C O U N T E R | .' fold '. .'|
|'. / counter \ | :::::::::::::::::::::::::::::: | / counter \ '|
|.' | .-----. | | still folding ...... | | .-----. | .'|
|'. | | C A U | | | turn 3 . 1 0 0 0 0 0 0 0 0 0 | | | C A U | | '|
|.' | | C A U | | | x 10^9 ......... [ no exit ] | | | C A U | | .'|
|'. | | C A U | | | >> codon CAU repeating <<<< | | | C A U | | '|
|.' \ '-----' / | >> peptide length: still 0 >> | \ '-----' / .'|
|'. '._______.-' '-------------------------------' '._______.-' '|
|.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.'.|
|'.'. ___________ a pew, at the crypt edge : ___________ '.'.|
|.'. | PEW No.7 | ____ | PEW No.7 | .'.|
|'. |___________| ./ᐠ｡ꞈ｡ᐟ\. ...zzz... woke. still |___________| '|
|.' | | | ( asleep ) folding. slept again. | | | .'|
|'. | | | '--------' | | | '|
|.'._____|_____|_____|_________________________________________ __|_____|_____|____.'|
|;________________________________________________________________________________ ;|
""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""" wib&wob When
Has not led the front.
With
Backlinks
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